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选取我院2014年8月~2016年8月收治的100例下尿路症状合并勃起功能障碍患者。随机分为单药组和联合组各50例。单药组患者采取西地那非单药治疗,联合组则采取西地那非联合坦索罗辛治疗。观察对比两组患者治疗前后国际前列腺症状评分(IPSS)、勃起功能障碍国际指数(IIEF-5)及生活质量评分(QOL)评分,以及不良反应发生情况。结果两组患者治疗前IPSS评分、IIEF-5评分、QOL评分比较无明显差异(P>0.05),治疗后联合组各评分均明显优于单药组,差异有统计学意义(P<0.05);两组不良反应发生情况比较,差异无统计学意义(P>0.05)。下尿路症状合并勃起功能障碍采取西地那非联合坦索罗辛治疗,可以更好地改善前列腺症状与勃起功能,且安全性高。
100 cases of lower urinary tract symptoms complicated with erectile dysfunction admitted to our hospital from August 2014 to August 2016 were selected. Randomly divided into monotherapy group and combination group of 50 cases. The single drug group took sildenafil monotherapy, while the combination group took sildenafil combined with tamsulosin treatment. The scores of International Prostate Symptom Score (IPSS), International Index of Erectile Dysfunction (IIEF-5) and Quality of Life Score (QOL) were compared between the two groups before and after treatment, and the incidence of adverse reactions was observed. Results There was no significant difference in the scores of IPSS, IIEF-5 and QOL between the two groups before treatment (P> 0.05). After treatment, the scores in the combined group were significantly better than those in the single drug group (P <0.05) There was no significant difference between the two groups in the incidence of adverse reactions (P> 0.05). Lower urinary tract symptoms combined with erectile dysfunction to take sildenafil combined with tamsulosin treatment, can better improve prostate symptoms and erectile function, and high safety.