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应用选择性支气管动脉灌注化疗药治疗晚期肺癌,在国内已有报道。我们从1986年9月至1987年9月对14例晚期巨块型肺癌病人行支气管动脉灌注顺铂(CDDP)或顺铂+丝裂霉素(MMC)治疗,收到较为满意的近期疗效。现报告如下。资料和方法 14例肺癌中,男13例,女1例,年龄39～71岁。肺癌部位:右上叶5例(1例伴右上叶肺完全不张),右下肺2例,左上肺5例(1例伴左上肺叶完全不张);左下叶2例。14例患者的病理类型:鳞癌6例,腺癌6例,未分化癌2例。按1978年UICC肺癌TNM病期分类:T_2N_1M_0 3例,T_2N_2M_0 5例,T_2N_1M_1 2例,T_3N_1M_0 3例,T_3N_2M_0 1例,T_(?)N_1M_1 1例。13例纤支镜均有阳性发现。全部病例均摄有正侧位胸片和气管分叉断层片,4例摄有55°侧后倾斜断层片。
Selective bronchial arterial infusion chemotherapy for advanced lung cancer has been reported in China. From September 1986 to September 1987, we performed bronchial arterial infusion of cisplatin (CDDP) or cisplatin and mitomycin (MMC) in 14 patients with advanced massive lung cancer, and received relatively satisfactory short-term results. The report is as follows. Materials and Methods Among 14 cases of lung cancer, 13 were male and 1 female, aged 39-71 years old. Lung cancer sites: 5 cases in the right upper lobe (1 case with complete atelectasis in the right upper lobe), 2 cases in the right lower lobe, 5 cases in the left upper lobe (1 case with complete atelectasis in the left upper lobe), and 2 cases in the left lower lobe. The pathological types of 14 patients included 6 cases of squamous cell carcinoma, 6 cases of adenocarcinoma, and 2 cases of undifferentiated carcinoma. According to the 1978 UICC lung cancer TNM classification: T_2N_1M_0 3 cases, T_2N_2M_0 5 cases, T_2N_1M_1 2 cases, T_3N_1M_0 3 cases, T_3N_2M_0 1 case, T_ N_M_1. All 13 cases were positive for bronchoscopy. All cases were photographed with positive lateral chest radiograph and tracheal bifurcation slice, and 4 patients were photographed with 55° lateral posterior oblique slice.