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对42例喉鳞癌(女性2例’男性40例;全部病人均未接受过术前治疗),20例正常喉粘膜标本,进行了表皮生长因子受体(EGF-R)、雌激素受体(ER)、黄体酮受体(PR)、雄激素受体(AR)的检查。检测结果:喉肿瘤组织标本和正常喉粘膜组织标本都含有EGF-R,发现EGF-R含量水平前者较后者明显的高(P<0.05)。在肿瘤标本中检测显示ER、PR、AR水平是非常低的,发现肿瘤组和正常粘膜标本组之间类固醇激素受体水平无显著性差异,而且ER、PR和
Forty-two patients with laryngeal squamous cell carcinoma (40 female and 2 female) were enrolled in this study. None of the patients underwent preoperative treatment and 20 normal laryngeal mucosa specimens were examined for EGF-R, estrogen receptor (ER), progesterone receptor (PR) and androgen receptor (AR). The results showed that EGF-R was found in both laryngeal and normal laryngeal mucosa tissues, and the former was higher than the latter (P <0.05). The detection of tumor samples showed that the levels of ER, PR and AR were very low, and there was no significant difference in the level of steroid hormone receptor between the tumor group and the normal mucosa specimen group. Moreover, ER, PR and