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目的应用64层CT评价导致急性心脏事件(acute cardiac event,ACE)的管腔狭窄与非钙化斑块的特点。资料与方法随访40例经64层CT证实的冠状动脉非钙化斑块患者7~12个月,比较ACE患者和非ACE患者冠状动脉非钙化斑块的形态特点(斑块的长度、厚度、CT值、表面规则度)及管腔狭窄程度。结果40例患者中10例随访过程中发生ACE,占25%,其中9例管腔狭窄≥50%。ACE患者的非钙化斑块厚度(3.4±0.9)mm较非ACE患者的非钙化斑块厚度(2.5±0.7)mm增厚,差异有统计学意义(P<0.01),而ACE患者斑块的长度、CT值及表面规则度与非ACE患者的差异无统计学意义。结论管腔严重狭窄者ACE发生率升高,ACE患者的非钙化斑块较未发生ACE患者的非钙化斑块厚。
Objective To evaluate the characteristics of stenosis and non-calcified plaque in acute cardiac events (ACE) assessed by 64-slice CT. Materials and Methods 40 cases of non-calcified coronary arteries confirmed by 64-slice CT were followed up for 7-12 months. The morphological characteristics of non-calcified coronary arteries were compared between ACE and non ACE patients (plaque length, thickness, CT Value, surface regularity) and stenosis. Results Of the 40 patients, 10 cases were followed up with 25% ACE, of which 9 cases had stenosis ≥50%. The non-calcified plaque thickness (3.4 ± 0.9) mm in ACE patients was thicker than non-calcified plaque thickness (2.5 ± 0.7) mm in non-ACE patients (P <0.01) There was no significant difference in length, CT value and surface regularity between non-ACE patients and non-ACE patients. Conclusion The incidence of ACE in patients with severe stenosis is higher than that in non-calcified plaques in ACE patients.