肥胖病不仅解剖上脂肪组织增加。而且有一系列病理生理变化,本文就近几年来对该病研究的新成就综述如下: 一、能量代谢与体温调节的变化 肥胖者总摄氧量增加,但按单位体表面积计算则比正常低。除脂肪组织外,其它组织代谢率与正常人同。肥胖者对环境温度变化的应激反应低下。因为体温每升高1℃,基础代谢率要升高12%。所以肥胖者用于产热的能量消耗减少,将多余的能量以脂肪的形式贮存起来,形成或维持肥胖。动物实验发现,暴露于寒冷中的肥胖大鼠,肌细胞膜 Obesity not only anatomically increases adipose tissue. And there are a series of pathophysiological changes, this article in recent years, the new achievements of the disease research summarized as follows: First, the energy metabolism and thermoregulation changes Obese total oxygen uptake, but according to the unit body surface area is lower than normal. In addition to adipose tissue, the metabolic rate of other tissues with the normal person. Obese people’s stress response to changes in ambient temperature is low. Because the body temperature increased by 1 ℃, the basal metabolic rate should be increased by 12%. Therefore, obese people to reduce the energy consumption for heat production, the excess energy stored in the form of fat to form or maintain obesity. Animal experiments revealed that the exposed rat’s cold, obese rat muscle membrane