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头孢三嗪是一个长效、注射头孢菌素。截至1988年中期共有118篇文章报道了该药在儿科患者中的应用,观察了它在4743例病儿中所显示的效能及耐受性。其中,3725例次为:脑膜炎、败血症、下呼吸道感染、骨及软组织感染。败血症共有56篇文章报道642例病儿为败血症伴发热,或脓毒血症,418人确定为菌血症。表二显示了头孢三嗪治疗病儿的细菌学效果。曾有报道:371例败血症及(或)脓毒血接受头孢三嗪,1018例则应用传统的标准抗生素化疗作对照。头孢三嗪治疗的适应症及相应的反应率列于表一。从表一可看出:所有病种中最常见的依
Ceftriaxone is a long-acting, injectable cephalosporin. As of mid-1988 a total of 118 articles reported the use of this drug in pediatric patients and observed its efficacy and tolerability demonstrated in 4743 children. Among them, 3725 cases were: meningitis, septicemia, lower respiratory tract infection, bone and soft tissue infections. Sepsis A total of 56 articles reported 642 cases of sepsis with fever or sepsis and 418 confirmed as bacteremia. Table 2 shows the bacteriological effect of ceftriaxone treatment of sick children. It has been reported: 371 cases of sepsis and (or) sepsis received ceftriaxone, 1018 cases of conventional standard antibiotic chemotherapy as a control. Ceftriaxone treatment of the indications and the corresponding response rates are shown in Table 1. As can be seen from Table 1: the most common of all diseases