系统性红斑狼疮(SLE)的临床表现是多种多样的,常累及多个器官,且不同个体或同一个体在不同阶段其临床表现也可不同,特别在早期,往往仅有1～2个系统的症状,缺乏实验室检查的证据,要作出准确的诊断是较为困难的.1948年Hargraves等发现了狼疮细胞(LE细胞)后,对SLE的诊断起了很大作用.随着实验室技术的进步,间接免疫荧光法和酶标记技术用于抗核抗体的检查,使阳性率大为提 The clinical manifestations of systemic lupus erythematosus (SLE) are diverse and often involve multiple organs, and different individuals or the same individual in different stages of their clinical manifestations may also be different, especially in the early, often only 1-2 systems Of the symptoms, the lack of laboratory evidence, to make accurate diagnosis is more difficult to .1948 Hargraves and other found lupus cells (LE cells), the diagnosis of SLE played a significant role .As laboratory technology Progress, indirect immunofluorescence and enzyme labeling techniques for the detection of anti-nuclear antibodies, so that a large positive rate