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目的探讨能够有效预防冠心病发病的男性酒精日摄入量范围。方法采用问卷调查结合血脂检测的方法,对758例只有饮用白酒习惯的男性结果进行分析。按照血清高密度脂蛋白胆固醇(HDL-C)水平是否大于1.55mmol/L分为两组,分析两组酒精日均摄入量差异的显著性。然后采用逐渐递增的方法,分别按照不同水平的酒精摄入量分组,分析每种情况下酒精摄入量的差异性,以出现差异不再具有统计学意义的分组水平作为能够预防冠心病发病的男性日均酒精摄入量的上限。结果 HDL-C>1.55mmol/L和HDL-C≤1.55mmol/L两组的酒精日均摄入量分别为35.23g、21.35g,差异具有显著性(P<0.0005)。从35g的酒精日均摄入量逐渐递增到75g以上时,两组HDL-C水平的差异均具有显著性(P<0.001);当进一步递增至80g以上时,两组差异的显著性消失。结论男性酒精日均摄入量在35-80g之内时,可以起到有效预防冠心病发病的作用。
Objective To explore the range of daily intake of male alcohol that can effectively prevent the onset of coronary heart disease. Methods A questionnaire survey combined with the method of blood lipid test was used to analyze the results of 758 male patients who only used liquor. According to the level of serum high-density lipoprotein cholesterol (HDL-C) is greater than 1.55mmol / L divided into two groups, analysis of the two groups of significant differences in daily intake of alcohol. And then gradually increasing method, respectively, according to different levels of alcohol intake grouping, analysis of alcohol intake in each case the difference in the difference is no longer statistically significant group level as a preventive measure of coronary heart disease Men’s daily upper limit of alcohol intake. Results The daily intake of alcohol in HDL-C> 1.55mmol / L and HDL-C≤1.55mmol / L groups were 35.23g and 21.35g, respectively. The difference was significant (P <0.0005). When the average daily intake of 35g alcohol gradually increased to more than 75g, the HDL-C levels were significantly different between the two groups (P <0.001). When further increasing to above 80g, the differences between the two groups disappeared significantly. Conclusion The average daily intake of male alcohol within 35-80g, can play an effective role in preventing the pathogenesis of coronary heart disease.