肾毒性反应大部分抗生素是从肾脏排泄的.抗生素对肾脏的毒性有以下两种情况:抗生素直接损伤肾组织;或肾功能不全时,抗菌药物不能及时排出,使得药物在血液内及组织内逐渐蓄积,达到中毒剂量引起毒性反应.一般认为从尿中排出15%以下的抗生素,如红霉素、氯霉素、新霉素等,不受肾功能影 Nephrotoxic reaction most of the antibiotics are excreted from the kidneys.Antibiotics on the kidneys of the following two conditions: Antibiotics directly damage the renal tissue; or renal insufficiency, antimicrobial drugs can not be discharged in time, making drugs within the blood and tissue gradually Accumulation, to toxic dose caused toxic reactions.It is generally considered from the urine of less than 15% of antibiotics, such as erythromycin, chloramphenicol, neomycin, etc., from renal function