父母患有重性精神疾病的儿童是一个很大的群体,他们具有和常人不同的遗传基础和环境因素,是精神问题的高风险人群。但是,由于一些保护性因素的存在,仍然有许多儿童并未出现不利后果。儿童青少年不利结果常常是父母精神疾病与各种因素相互作用的结果,其影响机制是多层面的,包括广泛的气质性/遗传性与心理社会因素。已有的证据表明,针对父母有精神疾病的儿童进行干预能降低罹患风险。本文通过梳理文献,综述了国内外研究成果,提出了现有研究的局限及未来基于中国文化背景下的研究主题。 Children with parents with severe mental illness are a large group of parents who have a different genetic basis and environmental factors than ordinary people and are at high risk of mental problems. However, many children still did not have adverse consequences due to some protective factors. Disadvantaged outcomes for children and adolescents are often the result of interactions between parents’ mental illnesses and various factors, and their mechanisms of influence are multifaceted and include a wide range of temperamental / hereditary and psychosocial factors. There is already evidence that interventions targeting children with mental illness can reduce the risk of developing the disease. This paper reviews the literature, summarizes the research results at home and abroad, puts forward the limitation of existing research and the future research theme under the background of Chinese culture.