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流行病学调查用虫卵计数作为感染度指数,曾发现有明显症状如肝肿大和脾肿大者只见于一小部分感染较重的人群。同样,病理研究也指出肝纤维化只见于虫负荷较重的病人,而轻感染者病变甚为轻微。作者试用动物模型更明确地描述了感染度与病变的关系。仓鼠每组10只,分别皮下注射曼氏血吸虫尾蚴20、40、80或160条,另20只分别从皮肤感染尾蚴3条。感染后第5周起每周称体重1次,并观察有无死亡以及其他变化,第9周开始进行大便虫卵计数。结果发现尾蚴
Epidemiological survey using the egg count as the index of infection, it has been found that there are obvious symptoms such as hepatomegaly and splenomegaly seen only in a small part of the population with a higher prevalence. Similarly, pathological studies also indicate that hepatic fibrosis occurs only in patients with severe insect loads, whereas those with mild infections have a mild disease. The authors tried animal models to more clearly describe the relationship between infection and disease. Each group of 10 hamsters were subcutaneous injection of Schistosoma mansoni cercariae 20,40,80 or 160, and the other 20 were from the skin infected cercariae 3. Body weight was weighed once a week from the fifth week after infection and the presence or absence of death and other changes were observed. At the ninth week, stool egg count was started. The results found cercariae