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自从1968年Berger首次描述IgA肾病以来,日益认为这是一种独立的临床病理征候。其特点是在免疫荧光检查下,肾小球毛细血管系膜内有IgA及C_2的沉积。伴随反复发作的咽炎,患者有血尿。初期的观察认为此种情况是良性的,但近来对此又产生了疑问。有的文献指出其中有些病例后来发展为慢性肾衰需要血透或肾移植,而且移植肾可以有同样病情的复发。作者报告在澳大利亚成年人原发性肾小球疾病进行肾活检时,最常见的发现是IgA肾病,在412例肾活检中占143例(35%)。其中50例不存在其它全身性的疾患,另93例在血管系膜内虽然也有IgA,但不
Since 1968 Berger first described IgA nephropathy, it is increasingly recognized as an independent clinical pathological sign. It is characterized by immunofluorescence, glomerular capillary mesangial IgA and C 2 deposition. With recurrent pharyngitis, the patient has hematuria. Initial observations that the situation is benign, but has recently been in doubt. Some literature pointed out that some of these cases later developed into chronic renal failure need hemodialysis or kidney transplantation, and transplant kidney can have the same condition recurrence. The authors report that the most common finding when performing kidney biopsies on adult primary glomerular disease in Australia is IgA nephropathy, accounting for 143 (35%) of 412 renal biopsies. 50 cases of other systemic diseases do not exist, the other 93 cases in the vascular mesangial although there are IgA, but not