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人类核仁形成区(NOR)位于5对近端着丝粒染色体的副缢痕处,也是人类18S—28S rRNA 基因所在的位置。近几年通过银染技术能使 NOR 特异染色,并且证实只有在功能上有活性的NOR 才能被银染,因此银染技术被认为是目前探讨 rRNA 基因功能的准确方法。
The human nucleolar organizer region (NOR) is located at the side of the 5 pairs of proximal centromeric chromosomes and is also where the human 18S-28S rRNA gene is located. In recent years, silver staining has been used to specifically stain NOR, and it has been confirmed that only functionally active NOR can be stained with silver. Therefore, silver staining is considered as an accurate method for exploring the function of rRNA genes.