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炎症细胞释放多种介质,以复杂的方式相互影响,产生了哮喘气道的病理学特点。IL-6是近年来发现的一种细胞因子,不仅局部起作用,在病理状态下可大量分泌,进入血液循环,为临床检测提供了条件。本文观察了28例儿童支气管哮喘急性发作时血清IL-6的水平,以探讨其在儿童哮喘中的变化及意义。 材料和结果 一、对象 哮喘组28例,男18例,女10例,年龄1～7岁,平均4.5岁,均符合1993年第三届全国小儿呼吸道疾病学术会议制定的哮喘诊断标准。19例健康儿为对照组,男10例,女9例;年龄2～8
Inflammatory cells release a variety of mediators that interact in a complex manner and produce the pathological features of asthma airways. IL-6 is a cytokine found in recent years, not only local role in the pathological state can be secreted in large quantities, into the blood circulation, provided the conditions for clinical testing. This article observed 28 children with acute exacerbation of bronchial asthma serum IL-6 levels to explore its changes in children with asthma and its significance. MATERIALS AND RESULTS A. Subjects Asthma group consisted of 28 patients, 18 males and 10 females, aged from 1 to 7 years old with an average of 4.5 years old. All of them were in line with the diagnostic criteria for asthma developed by the 3rd National Pediatric Respiratory Disease Academic Conference in 1993. 19 healthy children as the control group, 10 males and 9 females; aged 2 ~ 8