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本文报告我院1964年至1984年4月,经病理证实的直肠平滑肌肉瘤6例,占本院同期直肠恶性肿瘤的0.77％,高于国外文献报告。本组男性4例、女性2例。年龄范围26～74岁,平均48.6岁。主要临床症状是扪及包块(6/6),肛门区域痛(5/6),直肠出血(4/6)和便秘(4/6)组织学诊断标准为瘤细胞明显异形。瘤细胞多形性及瘤巨细胞;最主要的是核分裂象(1/10PHF)以上。随访结果表明肿瘤直径较大,瘤细胞分化低及核分裂象多预后差。本文对直肠平滑肌肉瘤的鉴别诊断和预后因素作简要讨论。
This article reports that in our hospital from 1964 to April 1984, 6 cases of rectal leiomyosarcoma confirmed by pathology, accounting for 0.77% of the same period of this hospital rectal cancer, higher than foreign reports. This group of 4 males and 2 females. The age range is 26 to 74 years, with an average of 48.6 years. The main clinical symptoms were sputum and mass (6/6), pain in the anal area (5/6), rectal bleeding (4/6) and constipation (4/6). Tumor cell pleomorphism and tumor giant cells; the most important is the mitotic figure (1/10PHF) or more. The follow-up results showed that the tumor diameter was large, the tumor cells were poorly differentiated, and the mitotic pattern was as poor as possible. This article briefly discusses the differential diagnosis and prognostic factors of rectal leiomyosarcoma.