假肥大性肌营养不良症(Duchenne musculardystrophy,下称DMD)是一种多在儿童期发病,以肌肉进行性萎缩无力为临床特征,至今尚无有效治疗方法的致死性X伴性隐性遗传病。对其唯一有效的防治途径是通过产前诊断阻止患儿的出生。以往的检查是沿用分子杂交方法做胎儿的基因分析,但由于DMD基因巨大,分子杂交耗时费力,通常难以及时 Duchenne muscular dystrophy (hereinafter referred to as DMD) is a multi-morbid X-linked recessive disorder characterized by clinical manifestations of childhood atrophic muscular atrophy and no effective treatment. . The only effective way to prevent it is to prevent the birth of a child by prenatal diagnosis. In the past, the method of molecular hybridization was used to analyze the fetus. However, due to the large size of the DMD gene and the time-consuming molecular hybridization, it is often difficult to timely