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目的 :探讨平阳霉素治疗口腔颌面颈部淋巴管瘤的疗效和适应症。方法 :195例口腔颌面颈部淋巴管瘤患者的 2 0 0个瘤体采用平阳霉素瘤内局部注射治疗。毛细管型和海绵型淋巴管瘤在瘤体内作分点注射 ;囊肿型淋巴管瘤则抽出部分囊液后 ,再注射药液。治疗周期及用药量根据淋巴管瘤的部位、大小、类型和患者年龄而定。评价其治疗效果。结果 :总有效率为 5 4 5 % (10 9/ 2 0 0 ) ,其中囊肿型淋巴管瘤疗效最好 ,有效率为 10 0 % (5 1/ 5 1) ,而海绵型和毛细管型及其混合型的有效率分别为 4 6 36 % (5 1/ 110 ) ,16 6 6 % (3/ 18) ,19 0 5 % (4/ 2 1)。结论 :平阳霉素局部注射疗法可作为口腔颌面颈部淋巴管瘤 ,尤其是囊肿型淋巴管瘤的首选治疗方法。
Objective: To investigate the curative effect and indications of Pingyangmycin in the treatment of oral and maxillofacial lymphangioma. METHODS: Twenty-five of 195 patients with oral and maxillofacial lymphangioma were treated with local injection of pingyangmycin. Capillary and sponge lymphangioma in the tumor for sub-point injection; cystic lymphangioma is part of the cyst fluid drawn after the injection of liquid. Treatment cycle and dosage according to lymphangioma site, size, type and patient age may be. Evaluate the treatment effect. Results: The total effective rate was 54.5% (10 9/2 000). Cystic lymphangioma had the best curative effect and the effective rate was 100% (5 1/5 1). While sponge type and capillary type The effective rates of the mixed type were 466% (51/110), 166% (3/18) and 195% (4/2), respectively. Conclusion: Pingyangmycin local injection therapy can be used as the preferred treatment for oral and maxillofacial lymphangioma, especially cystadenoma.