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作者评价严重下丘脑闭经患者中 LHRH 皮下脉动式给药诱发排卵的有效性。本研究选择3例中-重度下丘脑性继发闭经对克罗米芬150mg 无反应的不孕志愿者:a)闭经一年以上。b)口服孕激素5天无撤退性出血。c)以前检查宫颈粘液无羊齿植物叶状结晶和拉丝反应。d)LH 和 FSH 低于正常水平的低限。e)静脉给 LHRH10μg 无促性腺激素上升。所有可能影响生育的因素均在正常范围,包括子宫输卵管造影,精液分析、性交后试验和腹腔镜检查。无溢乳或催乳素增高,
The authors evaluate the effectiveness of subcutaneous pulsatile LHRH-induced ovulation induction in patients with severe hypothalamic amenorrhea. This study selected 3 cases of moderate-severe hypothalamic secondary amenorrhea clomiphene citrate 150mg non-responsive infertile volunteers: a) amenorrhea for more than a year. b) Oral progestin 5 days without withdrawal bleeding. c) previous inspection of cervical mucus without fern leaf phyllostachys and drawing reaction. d) Lower limit of LH and FSH below normal level. e) intravenous LHRH 10μg no gonadotropin rise. All of the factors that may affect fertility are in the normal range, including hysterosalpingography, semen analysis, sexual intercourse tests and laparoscopy. No galactorrhea or prolactin increased,