樟柳碱是从唐古特东茛菪植物(Scoplia tangutica)的地上部分提取分离出来的一个新生物碱。该植物在我国青海、西藏等省分布很广,资源丰富。青海民间称此植物为樟柳参,因此命名为樟柳碱。樟柳碱经临床试用,发现它在治疗眼底疾病、脑血管闭塞性疾病,促进昏迷患者苏醒、休克病人复合麻醉、急性有机磷农药中毒、偏头痛型血管性头痛以及抗晕动病等方面均具有一定的疗效。今将化学工作简略报道如下。将唐古特东茛菪茎叶粉碎,以乙醇热浸,浸液浓缩后除去叶绿素等杂质,碱化,用四氯化碳提取生物碱,转入酸水,调节至强碱性后用氯仿提取,蒸干得总碱,溶于无水乙醇,加氢溴酸至 Anisodine is a new alkaloid extracted from the aerial parts of Scoparia tangutica. The plant is widely distributed in our country Qinghai, Tibet and other provinces, rich in resources. Qinghai folk call this plant as camphor, so named as anisodine. Anisodine clinical trials found that it is in the treatment of retinal diseases, cerebrovascular occlusive disease, to promote the recovery of coma patients, shock patients with combined anesthesia, acute organophosphorus pesticide poisoning, migraine-like vascular headache and anti-motion sickness and so on Has a certain effect. The chemical work is briefly reported as follows. The Tanggut sclerotium stems and leaves were crushed to ethanol hot-dip, concentrated extract after removal of chlorophyll and other impurities, alkalization, extraction of alkaloids with carbon tetrachloride, transferred to acid water, adjusted to strong alkaline chloroform extraction , Evaporated to total alkalinity, dissolved in absolute ethanol, hydrobromic acid to