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目的:观察肺血栓栓塞症患者蛋白C活性的变化。方法:回顾性分析110例肺血栓栓塞症患者的临床资料,比较年龄≥60岁与<60岁患者,男、女性患者,维吾尔族与汉族患者蛋白C活性,蛋白C活性降低发生率。结果:(1)年龄≥60岁与年龄<60岁者蛋白C活性分别为83.0%、84.0%,差异无统计学意义(P>0.05);蛋白C活性降低发生率分别为32.3%、16.7%,差异有统计学意义(P<0.05)。(2)男、女患者蛋白C水平分别为83.0%、86.0%;蛋白C活性降低发生率分别为23.6%、31.6%,差异均无统计学意义(P>0.05)。(3)维吾尔族与汉族患者蛋白C活性分别为84.0%、83.0%,蛋白C活性降低发生率分别为19.5%、30.4%,差异均无统计学意义(P>0.05)。结论:老年人发生肺血栓栓塞症可能与蛋白C活性降低有关。
Objective: To observe the changes of protein C activity in patients with pulmonary thromboembolism. Methods: The clinical data of 110 patients with pulmonary thromboembolism were retrospectively analyzed. The incidences of protein C activity and protein C activity in patients aged 60 and older, male and female patients, Uygur and Han patients were compared. Results: (1) The activity of protein C was 83.0% and 84.0% respectively, with no significant difference (P> 0.05). The activity of protein C decreased 32.3% and 16.7% , The difference was statistically significant (P <0.05). (2) The levels of protein C in male and female patients were 83.0% and 86.0%, respectively. The incidence of protein C activity was 23.6% and 31.6%, respectively, with no significant difference (P> 0.05). (3) The protein C activity of Uygur and Han patients were 84.0% and 83.0%, respectively, and the incidence of protein C activity was 19.5% and 30.4% respectively, with no significant difference (P> 0.05). Conclusion: Pulmonary thromboembolism in the elderly may be related to the decrease of protein C activity.