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本文作者研究了50名麻风病人血清纤维蛋白溶解活力及其与各种不同型类麻风的关系.病人皆经临床、皮肤活组织及(或)鼻粘膜抹片检查而分型诊断.非瘤型组15名(其中结核样型10名,界线类5名);瘤型组25名;麻风反应10名(瘤型麻风发生反应者).并以15名健康个体为对照组.所有病人均除外肺结核、糖尿病、冠状动脉病、脑栓塞、肝硬化、类风湿关节炎和肾病.纤维蛋白溶解活力系采用优球蛋白溶解时间检测法测定,即采用Buckell法检测.结果:对照组和非瘤型组,其优球蛋白溶解时间相似,但瘤型麻风和麻风反应者优球蛋白溶解时间显著延长.与对照组比较有明显意义(P值为0.001).作者在讨论中称,本组非瘤型麻风其优球蛋白溶解时间无有意义的延长,但瘤型和麻风反应者则呈显有意义的延长,即纤维蛋白溶解活力降低.这种结果与其他作者所研究的相一致.
The authors studied the serum fibrinolytic activity of 50 leprosy patients and their association with different types of leprosy.All the patients were diagnosed by clinical, skin biopsy and / or nasal mucosal smear and diagnosed as non-neoplastic Group of 15 (including 10 tuberculosis samples and 5 boundary samples), 25 tumor patients, 10 leprosy patients (15 patients with leprosy) and 15 healthy individuals as control group, except for all patients Pulmonary tuberculosis, diabetes mellitus, coronary artery disease, cerebral embolism, cirrhosis, rheumatoid arthritis and nephropathy.Fibrinolytic activity was measured by euglobulin lysis time assay (Buckell’s method) .Results: Group, the euglobulin lysis time was similar, but the etioplasma lysis time of leprosy and leprosy patients was significantly longer, which was significantly higher than that of the control group (P = 0.001) .In the discussion, the authors said that this group of non-neoplasia Leprosy had no meaningful prolongation of its euglobulin lysis time, but the tumor type and leprosy responders showed a significant extension of the decrease in fibrinolytic activity, consistent with the results of other authors.