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对12例尿崩症患者(男女各6例)采用双盲法应用1-脱氨-8-右旋-精氨酸加压素(DDAVP)治疗5天的效果进行了观察分析。治疗期间每天收集24小时尿,测其总量及渗透压。结果显示治疗时尿量明显减少,尿渗透压增加,病人能很好耐受,无血压及心率变化。
In 12 patients with diabetes insipidus (6 males and 6 females), the effect of double-blind treatment with DDAVP for 5 days was observed and analyzed. 24 hours a day urine collected during treatment, measuring the total amount and osmotic pressure. The results showed that the urine output was significantly reduced and the urine osmolality was increased. The patient was well tolerated without blood pressure and heart rate changes.