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目的观察应用胺碘酮片口服治疗冠心病并发室性心律失常的效果及不良反应。方法随机将2014年12月至2016年12月收治的86例冠心病合并心律失常患者分为2组,每组43例。在常规治疗的基础上,对照组口服莫雷西嗪片治疗,观察组口服碘胺酮片治疗。比较两组的治疗效果。结果治疗后2组患者的心绞痛发作次数、心律改善幅度、心电图改善效果及总有效率均优于治疗前,但观察组的上述指标均显著优于对照组,差异有统计学意义(P<0.05)。两组均未发生药物不良反应。结论在常规治疗基础上应用碘胺酮片口服治疗冠心病合并室性心律失常,效果良好且无药物不良反应,可作为治疗冠心病合并室性心律失常的首选方法。
Objective To observe the effect and side effects of oral administration of amiodarone tablet in the treatment of coronary heart disease complicated with ventricular arrhythmia. Methods A total of 86 patients with coronary heart disease and arrhythmia admitted from December 2014 to December 2016 were randomly divided into two groups (43 in each group). On the basis of routine treatment, the control group orally took metoclopramide tablets and the observation group took orally Iammone tablets. Compare the treatment effect of two groups. Results After treatment, the number of angina attacks, the improvement of cardiac rhythm, the improvement effect of ECG and the total effective rate in both groups were better than those before treatment, but the above indexes in the observation group were significantly better than those in the control group (P <0.05 ). No adverse drug reactions occurred in both groups. Conclusion Oral administration of amiodarone tablet on the basis of routine treatment of coronary heart disease with ventricular arrhythmia, with good results and no adverse drug reactions, can be used as the treatment of coronary heart disease with ventricular arrhythmia preferred method.