乙酰胆碱酯酶(AChE,EC,3·1·1·7)广泛分布于人神经组织,还分布于人红细胞膜及血清等非神经组织.AChE 即是分泌型蛋白质,也是膜结合蛋白质,一般定位于细胞膜或突触前后膜,但某些细胞的亚细胞结构中也含有 AChE.已知在早老性痴呆患者脑组织某些区域,AChE 活性降低,在先天性神经管缺损胎儿羊水中 AChE 活性增高,但由于变性 AChE.的存在及可能的人红细胞膜 AChE 与假性胆碱酯酶的污染,在免疫组织化学及临床 AchE Acetylcholinesterase (AChE, EC, 3.1.1.7) is widely distributed in human nerve tissue, also distributed in human erythrocyte membrane and serum and other non-nerve tissue.AChE is a secreted protein, but also a membrane-bound protein, the general orientation AChE is also present in the subcellular structures of some cells.It is known that AChE activity decreases in some areas of brain tissue of patients with Alzheimer’s disease and that AChE activity is elevated in amniotic fluid of congenital neural tube defects , But due to the presence of denatured AChE. And possible human erythrocyte membrane AChE and pseudocholine esterase contamination in immunohistochemistry and clinical AchE