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目的:探讨过敏性结膜炎(AC)与抗过敏滴眼液用量间的关系,并分析季节因素对其产生的影响。方法:采用重力沉降法于2015年全年对北京城区主要气传花粉浓度进行监测,统计2015年我院变态反应科门诊AC就诊诊次及三种主要抗过敏滴眼液处方量,并采用Spearman相关性分析AC就诊诊次与抗过敏滴眼液用量间的关系。结果:2015年全年共监测花粉76164颗,花粉分布呈现春秋两季高峰,花粉分布最高的月份为4月(34.84%),其次为3月(29.72%),5月(10.87%),9月(10.52%),8月(9.94%);花粉分布最少的月份为1月和11月(0.11%)。春季花粉高峰期(3-5月份)月平均花粉数量为19150颗,秋季花粉高峰期(8-9月份)月平均花粉数量为7792颗,秋季花粉高峰期月平均花粉数量低于春季。2015年我院变态反应科AC月平均就诊诊次为(80.42±54.28)人次,8月份AC诊次最高,占全年的18.03%,其次为9月份(16.99%)、4月份(13.99%)、3月份(12.54%)、5月份(7.98%)。抗过敏滴眼液月平均用量为(148.67±148.63)瓶,8月份抗过敏滴眼液用量最高,占全年的28.25%,其次为3月份(17.21%)、9月份(14.18%)、4月份(13.11%)、5月份(8.30%),AC就诊次数及抗过敏滴眼液处方量均呈现春秋季节高峰。Spearman相关性分析显示,每月花粉量与AC就诊诊次、抗过敏滴眼液用量呈正相关(r=0.806,0.830,P=0.000,0.000),AC就诊诊次与抗过敏滴眼液用量呈正相关(r=0.923,P=0.000)。结论:花粉分布、AC诊次及抗过敏滴眼液用量均出现春秋季节高峰。秋季花粉致敏性高于春季花粉,用药及AC就诊最高峰均出现在秋季。
Objective: To investigate the relationship between allergic conjunctivitis (AC) and the amount of anti-allergic eye drops and to analyze the influence of seasonal factors on it. Methods: The main airborne pollen concentrations in urban areas of Beijing were monitored by gravity sedimentation method in 2015. The number of AC visits and three major anti-allergic eye drops in our department’s allergy clinic in 2015 were calculated. Spearman Correlation analysis The relationship between the frequency of AC visits and the amount of antiallergic eye drops. Results: In the whole year of 2015, 76,164 pollens were monitored. The pollen distribution showed the peak of spring and autumn. The month with the highest pollen distribution was April (34.84%), followed by March (29.72%), May (10.87%), Month (10.52%) and August (9.94%). The months with the least pollen distribution were January and November (0.11%). The average number of pollen per month in the spring pollen peak (March-May) was 19,150, while that in the autumn pollens peaked from August to September was 7,792. The average number of pollen per month in autumn pollen peak was lower than that in spring. The average number of AC visits per visit was (80.42 ± 54.28) in 2015, with the highest number of AC visits in August, accounting for 18.03% of the annual total, followed by September (16.99%), April (13.99%), , March (12.54%) and May (7.98%). The monthly average amount of anti-allergic eye drops was (148.67 ± 148.63) bottles. The amount of anti-allergic eye drops was the highest in August, accounting for 28.25% of the annual total, followed by March (17.21%), September (14.18%), Month (13.11%), May (8.30%), AC visits and anti-allergic eye drops prescription volume showed spring and autumn peak. Spearman correlation analysis showed that there was a positive correlation between the amount of pollen per month and the amount of anti-allergic eye drops (r = 0.806,0.830, P = 0.000,0.000) (R = 0.923, P = 0.000). Conclusion: The pollen distribution, the number of AC visits and the amount of anti-allergic eye drops all showed the peak in spring and autumn. Autumn pollen allergy than spring pollen, medication and AC peak were seen in the fall.