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本文研究了人免疫球蛋白(Ig)对非特异性溃疡性结肠炎(以下称结肠炎)病人大肠内菌丛的影响。作者共观察41例20～50岁结肠炎患者。结肠炎的诊断根据临床、X线和内窥镜资料。所有受检者分为病情相同的两个组。实验组29例病人,对照组12例。实验组病人肌注Ig,每次15ml,间隔48小时。共3次。对照组病人用皮质激素和柳氮磺胺吡啶代替Ig。治疗前(0天)和治疗后(第7天),用乙状结肠镜检查结肠粘膜,同时观察结肠内菌丛情况。按治疗前微生物数量的不同,将两组病人各分为3个亚组,按每克粪便所含菌体数分为:第1亚组10~6～10~7,第2亚组10~8,第3亚组10~9。
This article investigates the effect of human immunoglobulin (Ig) on the colonic flora in patients with nonspecific ulcerative colitis (hereinafter colitis). The authors observed a total of 41 patients aged 20 to 50 colitis. The diagnosis of colitis is based on clinical, radiographic and endoscopic data. All subjects were divided into two groups with the same disease. 29 patients in the experimental group and 12 in the control group. The experimental group of patients with intramuscular Ig, each 15ml, 48 hours apart. A total of 3 times. Control group of patients with corticosteroids and sulfasalazine instead of Ig. Before treatment (day 0) and after treatment (day 7), the colon mucosa was examined by sigmoidoscopy while the colonic flora was observed. According to the number of microorganisms before treatment, the two groups of patients were divided into three subgroups, divided by the number of bacteria per gram of faeces: the first subgroup 10 ~ 6 ~ 10 ~ 7, the second subgroup 10 ~ 8, the third subgroup 10 ~ 9.