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近年来国内对清除血清HBV DNA及e抗原的治疗作了不少探索。LAK细胞作为一种过继免疫疗法用于治疗慢性乙型肝炎已有报导。笔者自1992年始用血细胞分离机CS—3000采集异体淋巴细胞,制备LAK细胞治疗慢性乙型肝炎29例,结果表明异体LAK细胞治疗付HBV DNA和e抗原有明显的清除作用。现报告如下。
In recent years, the removal of serum HBV DNA and e antigen treatment made a lot of exploration. The use of LAK cells as an adoptive immunotherapy for the treatment of chronic hepatitis B has been reported. Since 1992, the author collected allogeneic lymphocytes from CS-3000 cells and prepared LAK cells for treatment of 29 chronic hepatitis B. The results showed that allogeneic LAK cells could clear HBV DNA and e antigen effectively. The report is as follows.