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应用不同剂量（１００μｇ／ｄ，２００μｇ／ｄ）的国产黄体生成素释放激素－Ａ（ＬＨＲＨ－Ａ）治疗子宫内膜异位症６６例，其中Ⅰ期９例，Ⅱ期４７例，Ⅲ期１０例。合并不孕症２９例，子宫肌腺症１０例。结果表明，５００μｇ／ｄ组对卵巢内膜囊肿的疗效最佳，但对子宫腺肌症的效果不明显，停药后妊娠７例，占２４％（７／２９）。所用ＬＨＲＨ－Ａ的３种剂量均抑制Ｅ２，Ｐ，ＰＲＬ的分泌，使血中生殖激素下降，排卵抑制和卵巢内膜囊肿缩小，对血胆固醇有升高作用，临床主客观症状体征以５００μｇ／ｄ组变化最为明显。
Sixty-six cases of endometriosis were treated with different doses of luteinizing hormone releasing hormone-A (LHRH-A) at different doses (100μg / d and 200μg / d), including 9 cases of stage Ⅰ, 47 cases of stage Ⅱ, example. Combined infertility in 29 cases, 10 cases of adenomyosis. The results showed that the 500μg / d group had the best curative effect on ovarian endometrial cyst but had no obvious effect on adenomyosis. There were 7 cases (24%, 7/29) after the withdrawal of pregnancy. The three doses of LHRH-A all inhibited the secretion of E2, P and PRL, decreased blood reproductive hormones, ovulation inhibition and ovarian cyst shrinkage, had an elevated effect on blood cholesterol. Clinical subjective and objective symptoms and signs of 500μg / d group changes the most obvious.