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肿瘤细胞可在细胞表面表达新抗原、刺激机体产生体液免疫反应,因此,在肿瘤病人血清中经常能检测到抗原抗体复合物的存在。免疫复合物也可能因其他因素所致,但与肿瘤相关的免疫复合物仅占免疫复合物总量中的一小部分,因此抗原非特异的免疫复合物的测定对肿瘤的早期诊断和预后常常得出自相矛盾的结果。所以,测定癌病人血清中抗原特异性免疫复合物可为鉴定肿瘤抗原提供一种方法并可用于判定肿瘤预后。
Tumor cells can express new antigens on the cell surface and stimulate the body to produce humoral immune responses. Therefore, the presence of antigen-antibody complexes can often be detected in tumor patient sera. Immune complexes may also be due to other factors, but tumor-associated immune complexes only make up a small part of the total immune complex. Therefore, the determination of antigen-non-specific immune complexes is often an early diagnosis and prognosis of tumors. Contradictory results. Therefore, measuring antigen-specific immune complexes in the serum of cancer patients can provide a method for identifying tumor antigens and can be used to determine the prognosis of tumors.