目的　观察早期应用小剂量多巴胺治疗新生儿缺氧缺血性脑病 (HIE)的疗效。方法　在常规治疗基础上 ,治疗组患儿早期应用多巴胺 5μg·kg- 1 ·min- 1 静脉滴注。结果　治疗组疗效显著优于对照组 ,P<0 0 1 ,治疗组患儿治疗 5～ 7d后全部痊愈出院。结论　早期应用小剂量多巴胺治疗新生儿缺氧缺血性脑病可降低病死率 ,缩短疗程 Objective To observe the effect of early application of small dose of dopamine on neonatal hypoxic-ischemic encephalopathy (HIE). Methods On the basis of routine treatment, dopamine 5μg · kg-1 · min-1 was infused intravenously in the treatment group. Results The treatment group was significantly better than the control group, P <0 01, the treatment group of children treated 5 ~ 7d after all were discharged. Conclusion The early application of low-dose dopamine in neonatal hypoxic-ischemic encephalopathy can reduce mortality and shorten the course of treatment