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成人ANLL115例,用DA方案(DAta)诱导治疗24例.HOAP方案(普通组)诱导治疗91例。结果:与普通组比较,DA组CR率收高(P=0.0369),但DA组感染率亦高(P=0.0091),且感染持续时间长(P=0.0022);化疗相关病死率也较高(P=0.0434);持续缓解时间及生存期两组差别无统计学意义。提示应根据客观条件选用诱导化疗方案。
Adult ANLL 115 patients were treated with DA (DAta) induction therapy in 24 cases. 91 cases were induced by HOAP regimen (ordinary group). Results: Compared with the normal group, the CR rate in the DA group increased (P=0.0369), but the DA group also had a high infection rate (P=0.0091) and a long duration of infection (P=0.0022); The related mortality was also high (P=0.0434); there was no significant difference between the two groups in duration of remission and survival. It is suggested that the induction chemotherapy regimen should be selected according to objective conditions.