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目的 :探讨脂蛋白 (a) [LP(a) ]及其它血脂成分在高海拔地区冠心病 (CHD)患者中的变化及相互关系 ;方法 :对 65例临床诊断的CHD患者和 40例对照者进行LP(a)测定和血脂检测分析 ;结果 :本组CHD患者中LP(a)明显高于正常对照组 (P <0 .0 1 ) ,两者之间差异有显著性 ,而TCH、HDL、LDL、TG测值基本正常 ,说明CHD患者中LP(a)的改变与其它血脂成分无相关性 ,敏感性及特异性高 ,进一步支持LP(a)为CHD的独立危险因素 ;结论 :LP(a)可作为诊断及预测高海拔地区CHD的一项重要指标。
Objective: To investigate the changes and correlations of lipoprotein (a) [LP (a)] and other lipid components in patients with coronary heart disease (CHD) at high altitude. Methods: Sixty-five CHD patients with clinical diagnosis and 40 controls LP (a) and serum lipids were analyzed. Results: The LP (a) in patients with CHD in this group was significantly higher than that in the normal control group (P <0.01), and there was significant difference between the two groups , LDL, TG values ?? were normal, indicating that the change of LP (a) in patients with CHD no correlation with other blood lipid components, high sensitivity and specificity, and further support LP (a) is an independent risk factor for CHD; Conclusion: LP (a) Can be used as an important indicator of diagnosis and prediction of CHD in high altitude areas.