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本文对62例冠心病患者进行了 HLA—A、B 抗原分型,全部为汉族,其中58例原籍北方。选100例河北省籍无亲缘关系汉族献血员做为对照组。结果发现冠心病组的 HLA-B13,B17及B27抗原频率显著增高。校正 P 值后 B13,B17抗原与对照组无显著差异,而 B27抗原仍呈显著差异,故可能与冠心病密切相关。所得结果与某些国外学者的报告相似,值得进一步研究。
In this paper, 62 patients with coronary heart disease were HLA-A, B antigen typing, all Han, of which 58 cases of origin North. Selected 100 cases of unrelated Han nationality blood donors in Hebei Province as a control group. The results showed that coronary heart disease group HLA-B13, B17 and B27 antigen frequency was significantly higher. There was no significant difference between B13 and B17 antigen and control group after P value was corrected, but B27 antigen still showed significant difference, so it may be closely related to coronary heart disease. The results obtained are similar to those of some foreign scholars and deserve further study.