【摘 要】
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Main observation and conclusionrnTwo new bis-quinolizidine alkaloids,neopetrosiasins A (1) and B (2),possessing cis-and trans-quinolizidine nuclei,one known rel
【机 构】
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Key Laboratory of Marine Drugs,The Ministry of Education of China,School of Medicine and Pharmacy,Oc
论文部分内容阅读
Main observation and conclusionrnTwo new bis-quinolizidine alkaloids,neopetrosiasins A (1) and B (2),possessing cis-and trans-quinolizidine nuclei,one known related analogue petrosin (3) and three known xestospongins (4-6),were isolated from the South China Sea sponge Neopetrosia chaliniformis.The structures of new compounds were unambiguously determined by extensive spectroscopic and single-crystal X-ray analyses.In bioassay,compounds 4-6 exhibited moderate cytotoxicity against several human cancer cells.
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