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２６例伴有发作性症状的多发性硬化（ＭＳ），占同期ＭＳ住院患者的２１．５％（２６／１２１）。其中癫痫（１１例）和痛性强直（９例）是较常见的发作类型，而发作性复视、三叉神经痛、猝倒、发作性视力障碍、瘙痒及构音障碍等则相对少见。这些发作性症状的共同特点是症状突然发生，突然停止，持续时间短暂，呈刻板式反复发作，有的可以是ＭＳ的首发症状。可能的发病机理是由于中枢神经系统脱髓鞘损害，使神经轴索纤维间冲动发生横向扩散所致。卡马西平等抗痉药物多可控制发作。
Twenty-six patients with multiple sclerosis (MS) who had seizure symptoms accounted for 21.5% (26/121) of MS inpatients during the same period. Among them, epilepsy (11 cases) and painful rigidity (9 cases) are the most common types of seizures, while episodic diplopia, trigeminal neuralgia, cataplexy, narcolepsy, pruritus and dysarthria are relatively rare. The common feature of these episodic symptoms is the sudden onset of symptoms, a sudden stop, short duration, a recurring stereotype, and some may be the first symptom of MS. The possible pathogenesis is due to demyelination of the central nervous system damage, so that the axial axonal fibers impulse lateral diffusion. Carbamax equal antispasmodic drugs can control the attack.