Huntington舞蹈病是以慢性进行性舞蹈样动作和痴呆为其特征的家族遗传性疾病,国内较为少见,现将我们1994年11月遇到的1例,结合其家系调查,报告如下.1 病例报告先证者(Ⅲg),女,44岁,大专文化,山东省郓城县人.因敏感多疑10年,进行性颈部、躯干及四肢不自主扭转舞动2年来我科就诊.患者于1984年4月无何原因地缓慢发病,表现孤僻、少语、多疑、害怕、失眠,有时自语自笑,病情渐加重,不能正常上班.于1988年、1989年先后2次住本院诊治,均诊为“精神分裂症”,给予氯氮平、氯丙嗪等系统治疗,精神症状有所 Huntington chorea is a familial inherited disease characterized by chronic progressive choreography and dementia. It is rare in China. One of the cases we encountered in November 1994, combined with its pedigree investigation, is as follows: 1 Case report The proband (Ⅲg), female, 44 years old, college culture, Tancheng County, Shandong Province .Because of sensitive and suspicious 10 years, progressive neck, torso and limbs involuntary twisting dance 2 years in our department .Patients in 1984 April no reason to slow onset, the performance of eccentric, absentminded, suspicious, afraid, insomnia, and sometimes self-laughing, the condition gradually increased, can not work .In 1988, 1989 has 2 times in our hospital for diagnosis and treatment, both Diagnosed as “schizophrenia”, given clozapine, chlorpromazine and other systemic treatment, mental symptoms