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观察病毒性乙型肝炎259例,96%发现病毒标志(HBsAg,抗-HBs,抗-HBc IgM)。急性肝炎187例(轻型45例,中型94例,重型48例)。慢性肝炎72例:慢性迁延性肝炎17例,慢性活动性肝炎51例(硬化期10例),肝硬化癌变4例。检查血清补体C3、α2-巨球蛋白、IgG 和前白蛋白水平的动态变化,评定各个指标之间的相互关系。结果轻、中、重型急性肝炎,在黄疸期第2周,C3水平都明显高于正常。但轻型肝炎在第5周C3水平恢复正常,而中、重型在第6周C3水平仍高。如果发病后前3周HBsAg 水平波动很大,有可能HBsAg 久存发展为慢性肝炎的病例,C3水平在全病
259 cases of viral hepatitis B were observed, and 96% of them were found to be virus markers (HBsAg, anti-HBs, anti-HBc IgM). Acute hepatitis 187 cases (45 cases of light, 94 cases of medium, heavy 48 cases). 72 cases of chronic hepatitis: 17 cases of chronic persistent hepatitis, 51 cases of chronic active hepatitis (sclerosis in 10 cases), cirrhosis of the liver in 4 cases. Check the dynamic changes of serum complement C3, α2-macroglobulin, IgG and prealbumin levels to assess the relationship between the various indicators. Results In mild, moderate and severe acute hepatitis, C3 levels were significantly higher than normal in the second week of jaundice. However, the level of C3 in the mild hepatitis returned to normal in the fifth week, while the level of C3 in the middle and heavy type was still high in the sixth week. If the first 3 weeks after the onset of HBsAg levels fluctuate greatly, it is possible that HBsAg long-standing development of chronic hepatitis, C3 levels in the whole disease