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肾脏疾病特别是其中发病率最高的肾小球肾炎,除急性肾炎极期和出现肾病综合征以及肾功衰竭末期外,多数患者在发病过程中并无浮肿发生。但在日常诊疗工作中,却可看到不少肾小球肾炎患者自诉早起及傍晚有面部、手足肿胀。它提示如有肾小球病变,即使尚无足以引起持续性浮肿发生的慢性钠代谢障碍,也可能有一过性钠排泄障碍存在。本文就成人中最多见的系膜增殖型肾炎对钠排泄急性调节的影响进行论述。1.系膜增殖与立位负荷时钠排泄的动态变化作者以肾活检有系膜增殖的肾炎患者为受试对象,采用静的立位负荷作为钠排泄减低的急性刺激,
Kidney diseases, especially the glomerulonephritis with the highest incidence, except for the acute phase of nephritic syndrome and nephrotic syndrome and the end of renal failure, most patients have no edema during the onset of the disease. However, in the daily diagnosis and treatment work, we can see many patients with glomerulonephritis get up early and evening face, hand and foot swelling. It suggests that if there is a glomerular lesion, there may be a transient sodium excretion disorder even though there are no chronic sodium metabolic disorders that are sufficient to cause persistent edema. This article discusses the most common adult mesangial proliferative nephritis on acute excretion of sodium excretion. 1. Mesangial proliferation and dynamic changes of sodium excretion at stand-up load The subjects with renal biopsy mesangial proliferation of nephritis patients as subjects, the use of static standing load as an acute reduction of sodium excretion stimulation,