胰腺的胰岛在糖尿病发病机制中的作用,为Minkowski摘出胰脏的动物试验所确定,并为Panting及Best发现胰岛素所证实。但在糖尿病病理生理学中,至今尚有许多未被阐明的问题。近年,对高血糖素在糖尿病产生中的作用予以很大注意。提出假说,认为糖尿病是由胰岛素缺乏和高血糖素过剩所引起的 The role of the pancreatic islets in the pathogenesis of diabetes, as determined by animal experiments in the Minkowski extirpation of the pancreas, was confirmed by both Panting and Best finding of insulin. However, in the pathophysiology of diabetes, there are still many unsolved problems. In recent years, much attention has been given to the role of glucagon in the development of diabetes. Put forward the hypothesis that diabetes is caused by insulin deficiency and glucagon excess