目的探讨广西40岁以上人群全死因构成比及影响因素。方法在1991年全国高血压调查的基础上,对广西40岁以上的11 526人进行随访调查,到死亡者死亡时所在医院核实死因,取得其全死因资料。结果死因顺位1~6位的疾病分别是脑卒中、肺部疾病、癌症、原因不明的死亡、心肌梗塞及消化性疾病。全死因COX回归分析表明,舒张压每增高1 mmHg,总的死亡相对危险度增加0.01;收缩压增高未对总死因产生影响;吸烟者的总的死亡相对危险度是不吸烟者的1.48倍;有心肌梗塞史者的总死亡相对危险度是无心肌梗塞者的3.11倍;有脑卒中史者的总死亡相对危险度是无脑卒中史者的1.95倍;男性比女性的总死亡发生率高。各死亡原因的COX回归分析表明,血压升高增加脑卒中、冠心病、癌症和糖尿病的相对死亡危险;吸烟增加冠心病、脑卒中、呼吸性疾病、癌症死亡的相对危险;体重指数升高增加脑卒中、冠心病及癌症死亡的相对危险。结论高血压、吸烟、有心肌梗塞及脑卒中史、男性人群是中老年人总死亡的危险因素。 Objective To investigate the constituent ratios of all causes of death and its influencing factors in Guangxi people over the age of 40. Methods Based on the National Hypertension Survey in 1991, 11 526 people over the age of 40 in Guangxi were investigated for follow-up. The cause of death was confirmed at the hospital where the deceased died, and all the causes of death were obtained. Results The first to sixth death causes were stroke, lung disease, cancer, unexplained death, myocardial infarction and digestive diseases. All-cause COX regression analysis showed that for each 1 mmHg increase in diastolic blood pressure, the relative risk of total death increased by 0.01; the increase of systolic blood pressure did not affect the total cause of death; the relative risk of total death among smokers was 1.48 times of that of non-smokers; The relative risk of total death with myocardial infarction was 3.11 times of those without myocardial infarction. The relative risk of total death with stroke history was 1.95 times of those with no history of stroke. The overall incidence of death in males was higher than that in females . COX regression analysis of the causes of death showed that elevated blood pressure increased the relative risk of death from stroke, coronary heart disease, cancer and diabetes; increased risk of coronary heart disease, stroke, respiratory disease, cancer death by smoking; increased body mass index Stroke, coronary heart disease and the relative risk of cancer death. Conclusions Hypertension, smoking, history of myocardial infarction and stroke, male population are the risk factors of total death in middle-aged and elderly people.