氯丙嗪在治疗应用上,常常引起患者兴奋的付作用,出现类似胆硷能神经兴奋的作用。偶然发现有一女婴儿患者服用氯丙嗪引起中毒死亡的病例,其与胆硷酯酶抑制剂如有机磷化合物引起的中毒症状非常相似,可看到眼睑肌肉纤维和四肢肌肉的自发性痉挛,经大白鼠实验认为氯丙嗪是很强的可逆性的胆硷酯酶抑制剂。 Chlorpromazine in the treatment of applications, often caused by the excitement of patients to pay the role of similar cholinergic nerve excitement. Occasionally, a baby girl who was treated with chlorpromazine to cause poisoning was found to have very similar symptoms of cholestatic esterase inhibitors such as those caused by organophosphorus compounds. Spontaneous spasms in muscle fibers and limb muscles of the eyelids were observed. Rat experiments that chlorpromazine is a strong reversible cholinesterase inhibitors.