已发现甲低大鼠胰腺的生长激素释放抑制因子(SRIF)增高,为此作者调查了甲低和甲亢病人的血浆SRIF。 尽管甲状腺是仅次于上消化道和胰腺的产生SRIF的最大器官,然而外周血中的SRIF主要来自上消化道和胰腺。为了比较甲低组和甲亢组病人血浆SRIF可能存在的差异,作者给病人输注精氨酸(它主要刺激胰腺释放SRIF),并比较了其它胰岛细胞激素血浆浓度的变化。 A hypothyroidism has been found in the pancreas of hypothyroidism, in which the authors investigated the plasma SRIF in patients with hypothyroidism and hyperthyroidism. Although thyroid is the largest organ producing SRIF after the upper digestive tract and the pancreas, SRIF in peripheral blood is mainly from the upper digestive tract and the pancreas. In order to compare the possible differences in plasma SRIF between patients with hypothyroidism and hyperthyroidism, the authors transfused arginine (which mainly stimulated the release of SRIF from the pancreas) and compared plasma concentrations of other islet cytokines.