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目的为了研究尿微量白蛋白在溃疡性结肠炎(UC)中的含量的变化及其临床意义。方法测定30例活动期溃疡性结肠炎患者的尿微量白蛋白分泌率(μg/min),并以20例健康成人做对照。结果UC组为10.36±13.14,对照组为2.74±1.26(P<0.05),直、乙状结肠组为6.30±6.88,降结肠组为7.25±2.52,横结肠以上组为17.52±15.49,各组间比较有明显差异(P<0.05),相关分析显示,r=0.45,P<0.05,即尿微量白蛋白含量与病变肠管长度呈正相关。结论尿微量白蛋白在UC活动期升高,其升高的程度与病变肠管的长度呈高度正相关。
Objective To study the changes of urinary albumin in ulcerative colitis (UC) and its clinical significance. Methods The urinary albumin excretion rate (μg / min) in 30 patients with active ulcerative colitis was measured and compared with 20 healthy adults. Results The UC group was 10.36 ± 13.14, the control group was 2.74 ± 1.26 (P <0.05), the straight group, sigmoid colon group was 6.30 ± 6.88, the descending colon group was 7.25 ± 2.52, and those in the group of transverse colon were 17.52 ± 15.49 (P <0.05). Correlation analysis showed that r = 0.45, P <0.05, ie urine Microalbumin content and pathological bowel length was positively correlated. Conclusions Urine microalbumin increased in the active stage of UC, and the degree of increase was positively correlated with the length of diseased intestine.