膀胱肉芽肿性炎症罕见,最常见的则是继发性结核病。作者首次报告一例浆细胞性肉芽肿。患者47岁,男性。排尿困难,下腹疼痛达三年,无肉眼血尿和尿路感染史。体格检查发现前列腺良性肥大,腹部耻骨右上有一直径约8 cm的无痛结实的肿块。实验室无明显异常发现,亦无镜下血尿。排泄性尿路造影和超声横断扫描确定肿块位于膀胱右上边缘,且与肥厚的膀胱壁相融合。膀胱镜检查显示有膀胱小梁和无蒂性肿块突入腔内,被盖粘膜完好。将肿块连同肥大的前列腺一并切除,冰冻切片示良性炎性病变。肿块9×3×7cm大小,界限清楚, Bladder granulomatous inflammation is rare, the most common is secondary to tuberculosis. The authors report for the first time a case of plasma cell granuloma. Patient 47 years old, male. Dysuria, abdominal pain up to three years, no gross hematuria and urinary tract infection history. Physical examination found benign prostatic hypertrophy, abdomen right supra pubis a diameter of about 8 cm painless solid mass. Laboratory no obvious abnormalities, no microscopic hematuria. Excretory urography and sonography confirmed that the mass was located at the upper right margin of the bladder and was associated with the hypertrophied bladder wall. Cystoscopy showed bladder trabecular and pedunculated mass into the cavity, the mucosa intact. Resection of the mass together with the enlarged prostate, frozen section showed benign inflammatory lesions. Mass 9 × 3 × 7cm size, clear boundaries,