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癌胚抗原(CEA)是20万分子重量(MW)的糖蛋白,由某些胚胎和成人组织,以及消化器官腺癌所分泌。原发和转移性结直肠肿瘤病人的广泛研究已明确,CEA的主要用途是通过术后周期性分析血清或血浆中的CEA,确定原发肿瘤切除后的局部和转移癌复发。Yeatman等新近发现浸溶于转移肿瘤部位体液的CEA值较血池中为高。由此启示人们分析结直肠癌肝转移病人的胆汁CEA值。这些研究证实,胆汁中CEA值明显高于血清中。线性回归分析表明,
Carcinoembryonic antigen (CEA) is a 200,000 molecular weight (MW) glycoprotein secreted by certain embryonic and adult tissues, as well as adenocarcinomas of the digestive tract. Extensive studies of patients with primary and metastatic colorectal cancers have made it clear that the primary use of CEA is to determine the local and metastatic cancer recurrence after primary tumor resection by periodically analyzing serum or plasma CEA after surgery. Yeatman et al. recently found that the CEA values of body fluids immersed in metastatic tumors are higher than those in blood pools. This inspires people to analyze bile CEA values in patients with colorectal liver metastases. These studies confirm that CEA values in bile are significantly higher than in serum. Linear regression analysis shows that