克山病病区分布于我国低硒地带 ,病区居民处于低硒状态 ,补硒可明显预防克山病发病。但单纯硒缺乏并不能说明克山病的全部临床流行病学特点 ,一些研究者曾提出在低硒状态下其它相关元素失衡的复合因素设想 ,并对比测定了病区和非病区人发中硒以外的其它元素含量 ,发现除硒外 , Keshan disease distribution in China’s low selenium zone, ward residents in a low selenium state, selenium can prevent Keshan disease. However, the lack of pure selenium does not account for all the clinical epidemiological features of Keshan disease. Some researchers have proposed a composite factor hypothesis that other related elements are imbalanced in the low selenium state. Other elements other than selenium content, found that in addition to selenium,