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噻吗心安(Timolol)是一种新型的β-受体阻断剂,它对β_1-和β_2-受体都具有阻断作用。口服较心得安的作用强5～10倍,且副作用较小,具有较好的降低眼内压作用。可以认为,自1954年使用醋唑磺胺降低眼压以来,噻吗心安的应用,在治疗青光眼的药物史中又是一次较新的进展。噻吗心安系白色结晶粉末,溶于水。对光、热稳定。噻吗心安容易透过角膜进入房水,在房水中的浓度可比血浆高出10多倍。噻吗心安有很好的降低眼压作用,无论对开角型、闭角型以及继发性青光眼都有效,被认为是目前最理想的治疗开角型青光眼的药物。特别是在应用其它药物无效时,应用本剂仍然有效,并对无晶体的青光眼效果也满意,对囊膜性青光
Timolol is a novel β-receptor blocker that blocks both β_1- and β_2-receptors. The effect of oral propranolol is 5 to 10 times stronger, with less side effects and better effect of reducing intraocular pressure. It is believed that the use of timolol has been a relatively new advance in the history of the treatment of glaucoma since it was used in 1954 to reduce intraocular pressure. Timothy heart security system is a white crystalline powder, soluble in water. Light, heat stable. Trithotrine easy access to aqueous humor through the cornea, aqueous humor concentration can be higher than the plasma 10 times. Timolol has a good ocular hypotensive effect, both open-angle, angle-closure and secondary glaucoma are effective, is considered to be the best current treatment of open-angle glaucoma drugs. Especially in the application of other drugs ineffective, the application of this agent is still valid, and the effect of non-crystalline glaucoma, the capsule glaucoma