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在正常情况下,人体内不会出现高半胱氨酸含量升高的情况,因为人体内不间断的反应可以把高半胱氨酸转化为另一种叫做蛋氨酸的物质,而该物质可以使基因中的DNA保持为正常的形态。 合理健康的膳食可以为人体提供维持这些反应正常所需要的若干物质。叶酸盐是一种B族维生素,它可以与高半胱氨酸结合生成蛋氨酸。体内叶酸盐的不足会降低这种反应并减少蛋氨酸的含量。这不利于DNA的生成和修补,而助长了非正常细胞的生成,进而发展成癌变。 即便是在对其它抗癌类营养物的摄取进行调节后,若干大型的研究已经显示,饮食中摄入高叶酸盐与低叶酸盐者相比较,前者患大肠腺瘤(即良性肿瘤)的危险性比后者低30～40％。研究提示,饮食中摄入叶酸盐较低者患乳腺癌、子宫癌、肺癌和食道癌的危险性也较高。
Under normal conditions, no increase in the homocysteine content occurs in the human body because the uninterrupted reaction in the human body converts homocysteine into another substance called methionine which, in turn, The DNA in the gene remains in its normal form. A reasonably healthy diet can provide the body with a number of substances needed to maintain these responses normal. Folic acid is a B vitamins that bind to homocysteine to produce methionine. Inadequate folic acid in the body reduces this reaction and reduces the methionine content. This is not conducive to DNA generation and repair, and contributed to the formation of abnormal cells, and then developed into cancer. Even after adjusting for the uptake of other anti-cancer nutrients, several large studies have shown that the former has colorectal adenomas (ie, benign tumors) when compared with those with low folate intake The risk is 30 ~ 40% lower than the latter. Research suggests that the lower folate intake in the diet is also associated with a higher risk of breast, uterine, lung, and esophageal cancers.