论文部分内容阅读
雷尼替丁(Ranitidine)引起肾损害,还未见文献报导。最近我院遇到1例,现报告于下。男,60岁,退休干部。间歇上腹疼痛10年,近2年加重。1986年9月16日我院纤维内窥镜检查诊断为十二指肠球部溃疡。曾服甲氰咪胍治疗,每次200mg,每日4次,10天后眼睑及下肢出现浮肿,无皮疹。停药后3天,浮肿消退。当时尿常规检查未见异常。1987年1月单用雷尼替丁治疗,每次150mg,每日2次,服药1周,自觉上腹痛明显改善,继续服药,服至21天,总量共6.3g时,自觉双手掌皮肢搔痒,出现皮疹,伴腰背胀痛,眼睑及下肢浮肿。既往无急、
Ranitidine caused renal damage, has not been reported in the literature. I recently encountered 1 hospital, the report is now under. Male, 60 years old, retired cadres. Intermittent abdominal pain for 10 years, nearly 2 years increased. September 16, 1986 our hospital fiber endoscopy diagnosis of duodenal ulcer. Cimetidine once served the treatment, each 200mg, 4 times a day, 10 days after the eyelids and lower extremities edema, no rash. Three days after stopping, edema subsided. Urine routine examination was normal. January 1987 alone with ranitidine treatment, each 150mg, 2 times a day, taking 1 week, consciously abdominal pain improved significantly, continue to take medicine, to 21 days, a total of 6.3g, the hands and hands consciously Pruritus, rash, back pain, eyelid and lower extremity edema. No urgency in the past