患者男性,44岁。因乏力、腹胀、恶心半年,于1984年9月17日入院。患者从事氯丁橡胶生产20年,工作岗位的氯丁二烯浓度历年常超过国家容许浓度数十倍,偶尔达数百倍(标准2mg/m~3),个人又不习惯戴防护口罩,于同年5月职业查体中发现肝大,肝功能不良收住院治疗。过去无氯丁二烯中毒史及病毒性肝炎史,无经常饮酒史。 Male patient, 44 years old. Due to fatigue, abdominal distension, nausea for six months, on September 17, 1984 admission. Patients engaged in the production of chloroprene rubber for 20 years, the concentration of chloroprene workplace over the years often exceed the national allowable concentration of several times, occasionally up to several hundred times (standard 2mg / m ~ 3), individuals are not accustomed to wearing protective masks, In May the same year found in occupational physical examination of liver, liver dysfunction received hospital treatment. In the past, there was no history of chloroprene poisoning and viral hepatitis, with no history of frequent alcohol consumption.